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CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusion.

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In benchmarks, this alternative can run anywhere between 2x to 120x faster than Web streams in every runtime I've tested it on (including Cloudflare Workers, Node.js, Deno, Bun, and every major browser). The improvements are not due to clever optimizations, but fundamentally different design choices that more effectively leverage modern JavaScript language features. I'm not here to disparage the work that came before — I'm here to start a conversation about what can potentially come next.

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